Publications (independent career)



44. Antifouling Polymers for Nanomedicine and Surfaces: Recent Advances

Eng, Y. J.; Nguyen, T. M.; Luo, H.-K.; Chan, J. M. W.*

Nanoscale 2023, 15, 15472-15512. PDF



43. Spotting Trends in Organocatalyzed and Other Organomediated (De)polymerizations and Polymer Functionalizations

Valle, M.; Ximenis, M.; Lopez de Pariza, X.; Chan, J. M. W.*; Sardon, H.*

Angew. Chem. Int. Ed. 2022, 61, e202203043. PDF



42. Progress in Spray-Coated Perovskite Films for Solar Cell Applications

Chou, L.-H.; Chan, J. M. W.*; Liu, C.-L.*

Solar RRL 2022, 6, 2101035. PDF



41. Direct Tracking Excited-State Intramolecular Charge Redistribution of Acceptor–Donor–Acceptor Molecule by Means of Femtosecond Stimulated Raman Spectroscopy

Zhang, W.; Xu, W.; Zhang, G.; Kong, J.; Niu, X.; Chan, J. M. W.*; Liu, W.*; Xia, A.*

J. Phys. Chem. B 2021, 125, 4456–4464. PDF



40. Symmetrical and Unsymmetrical Fluorine-Rich Ullazines via Controlled Cycloaromatizations

Zhang, G.; Gautam, P.; Chan, J. M. W.*

Org. Chem. Front. 2020, 7, 787–795. PDF



39. Pentafluorosulfanyl Group: An Emerging Tool in Optoelectronic Materials

Chan, J. M. W.*

J. Mater. Chem. C 2019, 7, 12822–12834. PDF

From the themed collection: Journal of Materials Chemistry C Emerging Investigators



38. Intramolecular Charge Transfer and Solvation Dynamics of Push-Pull Dyes with Different π-Conjugated Linkers

Niu, X.; Gautam, P.; Kuang, Z.; Yu, C. P.; Guo, Y.; Song, H.; Guo, Q.; Chan, J. M. W.*; Xia, A.*

Phys. Chem. Chem. Phys. 2019, 21, 17323-17331. PDF



37. Pentafluorosulfanylated Polymers as Electrets in Nonvolatile Organic Field-Effect Transistor Memory Devices

Zhang, G.; Lee, Y.-J.; Gautam, P.; Lin, C.-C.; Liu, C.-L.; Chan, J. M. W.*

J. Mater. Chem. C 2019, 7, 7865-7871. (Inside front cover) PDF



36. Water-Dispersible Bismuth‒Organic Materials with Computed Tomography Contrast Properties

Zhang, G.; Naha, P. C.; Gautam, P.; Cormode, D. P.; Chan, J. M. W.*

ACS Appl. Bio Mater. 2018, 1, 1918-1926. PDF



35. Using the Negative Hyperconjugation Effect of Pentafluorosulfanyl Acceptors to Enhance Two-Photon Absorption in Push-Pull Chromophores

Gautam, P.; Wang, Y.; Zhang, G.; Sun, H.; Chan, J. M. W.*

Chem. Mater. 2018, 30, 7055-7066. PDF



34. Pulling with the Pentafluorosulfanyl Acceptor in Push-Pull Dyes

Gautam, P.; Yu, C. P.; Zhang, G.; Hillier, V. E.; Chan, J. M. W.*

J. Org. Chem. 2017, 82, 11008-11020. PDF



33. Reversibly Thermochromic Bismuth-Organic Materials with Tunable Optical Gaps

Zhang, G.; Chan, J. M. W.*

J. Mater. Chem. C 2017, 5, 10007-10015. PDF




32. Sultam-based Hetero[5]helicene: Synthesis, Structure, and Crystallization-Induced Emission Enhancement

Virk, T. S.; Ilawe, N. V.; Zhang, G.; Yu, C. P.; Wong, B. M.; Chan, J. M. W.*

ACS Omega 2016, 1, 1336-1342. PDF


Publications (before independent career)

31. Highly Potent Antimicrobial Polyionenes with Rapid Killing Kinetics, Skin Biocompatibility and in vivo Bactericidal Activity

Liu, S.; Ono, R. J.; Wu, H.; Teo, J. Y.; Liang, Z. C.; Xu, K.; Zhang, M.; Zhong, G.; Tan, J. P. K.; Ng, M.; Yang, C.; Chan, J. M. W.; Ji, Z.; Bao, C.; Kumar, K.; Gao, S.; Lee, A.; Fevre, M.; Dong, H.; Ying, J. Y.; Li, L.; Fan, W.; Hedrick, J. L.; Yang, Y. Y.

Biomaterials 2017, 127, 36-48. PDF



30. Self-Assembled, Biodegradable Magnetic Resonance Imaging Agents: Organic Radical-Functionalized Diblock Copolymers

Chan, J. M. W.; Wojtecki, R. J.; Sardon, H.; Lee, A. L. Z.; Smith, C. E.; Shkumatov, A.; Gao, S.; Kong, H.; Yang, Y. Y.; Hedrick, J. L.

ACS Macro Lett. 2017, 6, 176-180. PDF



29. Organocatalytic Anticancer Drug Loading of Degradable Polymeric Mixed Micelles via a Biomimetic Mechanism

Chan, J. M. W.; Tan, J. P. K.; Engler, A. C.; Ke, X.; Gao, S.; Yang, C.; Sardon, H.; Yang, Y. Y.; Hedrick, J.

Macromolecules 2016, 49, 2013-2021. PDF.

Among Top 20 most read articles of Mar & Apr 2016.



28. Design and Synthesis of Biodegradable Grafted Cationic Polycarbonates as Broad Spectrum Antimicrobial Agents

Ong, Z. Y.; Coady, D. J.; Tan, J. P. K.; Li, Y.; Chan, J. M. W.; Hedrick, J. L.; Yang, Y. Y.

J. Polym. Sci., Part A: Polym. Chem. 2016, 54, 1029-1035. PDF.

Spotlight Article.



27. Thermoresponsive Random Poly(ether urethanes) with Tailorable LCSTs for Anticancer Drug Delivery

Sardon, H.; Tan, J. P. K.; Chan, J. M. W.; Mantione, D.; Mecerreyes, D.; Hedrick, J. L.; Yang, Y. Y.

Macromol. Rapid Commun. 2015, 36, 1761-1767. PDF



26. Broad-Spectrum Antimicrobial Polycarbonate Hydrogels with Fast Degradability

Pascual, A.; Tan, J. P. K.; Chan, J. M. W.; Coady, D. J.; Mecerreyes, D.; Hedrick, J. L.; Yang, Y. Y.; Sardon, H.

Biomacromolecules 2015, 16, 1169-1178. PDF



25. Hydrophilic Polycarbonates: Promising Degradable Alternatives to Poly(ethylene glycol)-based Stealth Materials

Engler, A. C.; Ke, X.; Gao, S.; Chan, J. M. W.; Coady, D. J.; Ono, R. J.; Lubbers, R.; Nelson, A.; Yang, Y. Y.; Hedrick, J. L.

Macromolecules 2015, 48, 1673-1678. PDF



24. Polyurethane-coated Silica Particles with Broad-Spectrum Antibacterial Properties

Xu, Q.; Sardon, H.; Chan, J. M. W.; Hedrick, J. L.; Yang, Y. Y.

Polym. Chem. 2015, 6, 2011-2022. PDF



23. Organocatalytic Ring-Opening Polymerization of Trimethylene Carbonate to Yield a Biodegradable Polycarbonate

Chan, J. M. W.*; Zhang, X.; Sardon, H.; Engler, A. C.; Fox, C. H.; Frank, C. W.; Waymouth, R. M.; Hedrick, J. L.

J. Chem. Educ. 2015, 92, 708-713. PDF



22. Antimicrobial Hydrogels: A New Weapon in the Arsenal against Multidrug Resistant Infections

Ng, V. W. L.; Chan, J. M. W.; Sardon, H.; Ono, R. J.; García, J. M.; Yang, Y. Y.; Hedrick, J. L.

Adv. Drug Deliv. Rev. 2014, 78, 46-62. PDF



21. Role of non-covalent and covalent interactions in cargo loading capacity and stability of polymeric micelles

Ke, X.; Ng, V. W. L.; Ono, R. J.; Chan, J. M. W.; Krishnamurthy, S.; Wang, Y.; Hedrick, J. L.; Yang, Y. Y.

J. Control. Release 2014, 193, 9-26. PDF



20. Overcoming Multidrug Resistance in Microbials Using Nanostructures Self-assembled from Cationic Bent-core Oligomers

Liu, S. Q.; Venkataraman, S.; Ong, Z. Y.; Chan, J. M. W.; Yang, C.; Hedrick, J. L.; Yang, Y. Y.

Small 2014, 10, 4130-4135. PDF



19. Chemically Modifiable N-Heterocycle-functionalized Polycarbonates as a Platform for Diverse Smart Biomimetic Nanomaterials

Chan, J. M. W.*; Ke, X.; Engler, A. C.; Sardon, H.; Yang, Y. Y.; Hedrick, J. L.

Chem. Sci. 2014, 5, 3294-3300. PDF

Among “Most downloaded articles” of July 2014.



18. Highly Tunable Polyurethanes: Organocatalyzed Polyaddition and Subsequent Post-polymerization Modification of Pentafluorophenyl Ester Sidechains

Sardon, H.; Chan, J. M. W.; Ono, R. J.; Mecerreyes, D.; Hedrick, J. L.

Polym. Chem. 2014, 5, 3547-3550. PDF



17. Organic Acid-Catalyzed Polyurethane Formation via a Dual-Activated Mechanism: Unexpected Preference of N-activation over O-activation of Isocyanates

Sardon, H.; Engler, A. C.; Chan, J. M. W.; García, J. M.; Coady, D. J.; Pascual, A.; Mecerreyes, D.; Jones, G. O.; Rice, J. E.; Horn, H. W.; Hedrick, J. L.

J. Am. Chem. Soc. 2013, 135, 16235-16241. PDF



16. Tetra-n-butylammonium Fluoride as an Efficient Transesterification Catalyst for Functionalizing Cyclic Carbonates and Aliphatic Polycarbonates

Chan, J. M. W.*; Sardon, H.; Engler, A. C.; García, J. M.; Hedrick, J. L.

ACS Macro Lett. 2013, 2, 860-864. PDF

Top 20 most read article of the month.



15. Polycarbonate-based Brush Polymers with Detachable Disulfide-linked Side Chains

Engler, A. C.; Chan, J. M. W.; Fukushima, K.; Coady, D. J.; Yang, Y. Y.; Hedrick, J. L.

ACS Macro Lett. 2013, 2, 332-336. PDF



14. Homogeneous Isocyanate- and Catalyst-free Synthesis of Polyurethanes in Aqueous Media

Sardon, H.; Engler, A. C.; Chan, J. M. W.; Coady, D. J.; O’Brien, J. M.; Mecerreyes, D.; Yang, Y. Y.; Hedrick, J. L.

Green Chem. 2013, 15, 1121-1126. PDF



13. Accessing New Materials Through Polymerization and Modification of a Polycarbonate with a Pendant Activated Ester

Engler, A. C.; Chan, J. M. W.; Coady, D. J.; O’Brien, J. M.; Sardon, H.; Nelson, A.; Sanders, D. P.; Yang, Y. Y.; Hedrick, J. L.

Macromolecules 2013, 46, 1283-1290. PDF



12. Studies on the Vanadium-Catalyzed Nonoxidative Depolymerization of Miscanthus giganteus-derived Lignin

Chan, J. M. W.; Bauer, S.; Sorek, H.; Sreekumar, S.; Wang, K.; Toste, F. D.

ACS Catal. 2013, 3, 1369-1377. PDF



11. Tandem Cycloisomerization/Suzuki Coupling of Arylethynyl MIDA Boronates

Chan, J. M. W.; Amarante, G. W.; Toste, F. D.

Tetrahedron 2011, 67, 4306-4312. PDF

Front cover article.



10. Synthesis of Stair-stepped Polymers Containing Dibenz[a,h]anthracene Subunits

Chan, J. M. W.; Kooi, S. E.; Swager, T. M.

Macromolecules 2010, 43, 2789-2793. PDF



9. Synthesis of J-Aggregating Dibenz[a,j]anthracene-Based Macrocycles

Chan, J. M. W.; Tischler, J. R.; Kooi, S. E.; Bulovic, V., Swager, T. M.

J. Am. Chem. Soc. 2009, 131, 5659-5666. PDF



8. Synthesis of Arylethynylated Cyclohexa-m-phenylenes via Sixfold Suzuki Coupling

Chan, J. M. W.; Swager, T. M.

Tetrahedron Lett. 2008, 49, 4912-4914. PDF



7. Bisphosphonate Inhibitors of ATP-mediated HIV-1 Reverse Transcriptase Catalyzed Excision of Chain-terminating 3′-azido, 3′-deoxythymidine: A QSAR Investigation

Song, Y.; Chan, J. M. W.; Tovian, Z.; Secrest, A.; Nagy, E.; Krysiak, K.; Bergan, K.; Parniak, M. A.; Oldfield, E.

Bioorg. Med. Chem. 2008, 16, 8959-8967. PDF



6. Inhibition of Trypanosoma cruzi Hexokinase by Bisphosphonates

Hudock, M. P.; Sanz-Rodriguez, C. E.; Song, Y.; Chan, J. M. W.; Zhang, Y.; Odeh, S.; m/wpKosztowski, T.; Leon-Rossell, A.; Concepcion, J. L.; Yardley, V.; Croft, S. L.; Urbina, J. A.; Oldfield, E.

J. Med. Chem. 2006, 49, 215-223. PDF



5. Bisphosphonate Inhibition of the Exopolyphosphatase Activity of the Trypanosoma brucei Soluble Vacuolar Pyrophosphatase

Kotsikorou, E.; Song, Y.; Chan, J. M. W.; Faelens, S.; Tovian, Z.; Broderick, E.; Bakalara, N.; Docampo, R.; Oldfield, E.

J. Med. Chem. 2005, 48, 6128-6139. PDF



4. Pyridinium-1-yl Bisphosphonates are Potent Inhibitors of Farnesyl Diphosphate Synthase and Bone resorption

Sanders, J. M.; Song, Y.; Chan, J. M. W.; Jennings, S.; Zhang, Y.; Kosztowski, T.; Odeh, S.; Flessner, R.; Kotsikorou, E.; Meints, G.; Gomez, A. O.; Gonzalez-Pacanowska, D.; Raker, A. M.; Wang, H.; Morita, C. T.; Oldfield, E.

J. Med. Chem. 2005, 48, 2957-2963. PDF



3. Bisphosphonate Inhibitors of Toxoplasma gondi Growth: In Vitro, QSAR and In Vivo Investigations

Ling, Y.; Sahota, G.; Odeh, S.; Chan, J. M. W.; Araujo, F. G.; Moreno, S. N. J.; Silvia, N. J.; Oldfield, E.

J. Med. Chem. 2005, 48, 3130-3140. PDF



2. Quantitative Structure-Activity Relationships for ɣ,δ T-Cell Activation by Bisphosphonates

Sanders, J. M.; Ghosh, S.; Chan, J. M. W.; Meints, G. A.; Wang, H.; Raker, A. M.; Song, Y.; Colantino, A.; Burzynska, A.; Kafarski, P.; Morita, C. T.; Oldfield, E.

J. Med. Chem. 2004, 47, 375-384. PDF



1. Effects of Bisphosphonates on the Growth of Entamoeba histolytica and Plasmodium Species in vitro and in vivo

Ghosh, S.; Chan, J. M. W.; Lea, C. R.; Meints, G. A.; Lewis, J. C.; Tovian, Z. S.; Flessner, R. M.; Loftus, T. C.; Bruchhaus, I.; Kendrick, H.; Croft, S. L.; Kemp, R. G.; Kobayashi, S.; Nozaki, T.; Oldfield, E.

J. Med. Chem. 2004, 47, 175-187. PDF


U.S. Patents

8. Chan, J. M. W.; Hedrick, J. L.; Ono, R. J.; Teo, J. Y.; Yang, Y. Y.; Zhang, M. S. “Antimicrobial Polymers Formed by Bulk Polyaddition”,
U.S. Patent 9,642,360, 2017.

7. Chan, J. M. W.; Wojtecki, R. J.; Hedrick, J. L.; Yang, Y. Y.; Lee, A. L. Z. “Biodegradable Organic Radical-Functionalized Polycarbonates
for Medical Applications”, U.S. Patent 9,718,951, 2017.

6. Breyta, G.; Chan, J. M. W.; Coady, D. J.; Engler, A. C.; Garcia, J. M.; Han, W.; Hedrick, J. L.; Liu, S.; Nelson, A.; Ono, R. J.; Teo, J. Y.; Yang, Y. Y.;
Zhang, M. S. “Condensation Polymerization for Antimicrobial Applications”, U.S. Patent 9,580,554, 2017.

5. Chan, J. M. W.; Engler, A. C.; Sardon, H.; Hedrick, J. L.; Yang, Y. Y. “Polycarbonates Bearing Aromatic N-Heterocycles for Drug Delivery”,
U.S. Patent 9,717,797, 2017.

4. Chan, J. M. W.; Coady, D. J.; Engler, A. C.; Garcia, J. M.; Hedrick, J. L.; Ong, Z. Y.; Sardon, H.; Yang, Y. Y. “Catalyst-free methods of forming
polyurethanes from pentafluorophenyl carbonates”, U.S. Patent 9,062,160, 2015.

3. Lin, B. F.; Chan, J. M. W.; Nelson, A.; Engler, A. C.; Hedrick, J. L.; Maune, H. “Irreversibly Degradable Polycarbonate-based Complex Coacervate”,
Patent Disclosure, 2014.

2. Sanders, J. M.; Song, Y.; Chan, J. M. W.; Oldfield, E.; Zhang, Y. “Bisphosphonate compounds and methods for bone resorption diseases, cancer,
bone pain, immune disorders and infectious diseases”, U.S. Patent 8,071,573, 2011.

1. Parniak, M.; Mellors, J. W.; Oldfield, E.; Tovian, Z.; Chan, J. M. W. “Composition and Methods for Use of Antiviral Drugs in the Treatment of
Retroviral Diseases Resistant to Nucleoside Reverse Transcriptase Inhibitors”, U.S. patent application 10/937,683, 2005.


Conferences and Invited Talks

16. Chan, J. M. W. “Sustainable and Green Materials: An Overview”. NTU-UChicago Joint Symposium, Singapore, February 2023, Invited.

15. Chan, J. M. W. “Masterclass: Grant Writing”. Institute of Chemical and Engineering Sciences, Singapore, January 2022, Invited.

14. Chan, J. M. W. 102nd Canadian Chemistry Conference and Exhibition, Quebec City, Canada, June 2019. “Innovative Concepts in Organic
Materials” Symposium. Invited.

13. Chan, J. M. W. 101st Canadian Chemistry Conference and Exhibition, Edmonton, Canada, 2018. “Emerging Materials Chemistry Investigator”
Symposium. Invited.

12. Chan, J. M. W. Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, USA, January 2018. Invited.

11. Chan, J. M. W. “Designing Sulfonamide-based π-conjugated Systems for Organic Electronics”, 100th Canadian Chemistry Conference and
Exhibition, Toronto, ON, Canada, 2017.

10. Chan, J. M. W. “Organic Electronic Materials via Molecular Design and Synthesis”, New Professors Lecture Program, Ottawa, ON, Canada,
2017. Invited.

9. Chan, J. M. W. “Designing Sulfonamide-based π-conjugated Systems for Organic Electronics”, 99th Canadian Chemistry Conference and
Exhibition, Halifax, NS, Canada, 2016.

8. Chan, J. M. W. “Introduction to the Synthesis of π-Conjugated Polymers”, National University of Singapore, 2014.

7. Chan, J. M. W.; Sardon, H.; Engler, A. C.; Hedrick, J. L. “Organocatalytic methods and postpolymerization modification strategies for functional
aliphatic polycarbonate synthesis”, 247th ACS National Meeting & Exposition, Dallas, TX, 2014.

6. Chan, J. M. W. “Design & Synthesis of Organic Materials: From Conjugated Macrocycles to Functional Polycarbonates”, UC Riverside, CA, 2014.

5. Chan, J. M. W. “Making and Breaking Macromolecules: From Electronic Materials to Biomass”, University talk, ARC, San Jose, CA, 2012.

4. Chan, J. M. W.; Swager, T. M. “Synthesis of Dibenz[a,j]anthracene-based J-aggregates”, MIT Research Symposium in Organic and Bioorganic
Chemistry, Cambridge, MA, 2009.

3. Chan, J. M. W.; Swager, T. M. “Synthesis of Functionalized Hexa-m-phenylenes”, 234th ACS National Meeting, Boston, MA, 2007.

2. Chan, J. M. W.; Swager, T. M. “Synthesis of Novel Kekulene-type Torands”, 21st International Liquid Crystal Conference, Keystone, CO, 2006.

1. Chan, J. M. W.; Oldfield, E. “Design and Synthesis of Pharmaceutical Bisphosphonates”, Colgate-Palmolive Symposium, Urbana, IL, 2002.


Contributed Articles

11. Tischler, J. R.; Akselrod, G. M.; Bradley, M. S.; Chan, J.; Young, E. R.; Nocera, D. G.; Swager, T. M.; Bulović, V. “Strong Light-Matter Coupling
Using Robust Non-cyanine Dye J-aggregate Material”, MTL Annual Research Report, 2009.

10. Swager, T. M.; Chan, J. M. W. “Dendron-Modified Multi-Wall Carbon Nanotubes”, SYNFACTS 2007, 2, 0158.

9. Swager, T. M.; Chan, J. M. W. “Stacked Conjugated Oligothiophenes”, SYNFACTS 2007, 1, 0039.

8. Swager, T. M.; Chan, J. M. W. “Preparation of Novel Tetrathia[7]helicenes”, SYNFACTS 2007, 1, 0038.

7. Swager, T. M.; Chan, J. M. W. “Preparation of N-Substituted Diaza[12]annulenes”, SYNFACTS 2006, 12, 1233.

6. Swager, T. M.; Chan, J. M. W. “Synthesis of Fluorescent Dialkynylboradiazaindacenes”, SYNFACTS 2006, 12, 1226.

5. Swager, T. M.; Chan, J. M. W. “Synthesis of Stackable Pseudo-Triphenylenes”, SYNFACTS 2006, 11, 1123.

4. Swager, T. M.; Chan, J. M. W. “Preparation of Thiaphlorins and Related Dyads”, SYNFACTS 2006, 11, 1117.

3. Swager, T. M.; Chan, J. M. W. “Synthesis of Polyvinylenephosphines”, SYNFACTS 2006, 10, 1016.

2. Swager, T. M.; Chan, J. M. W. “Synthesis of Thiadiazole-Containing Polycyclic Aromatic Systems”, SYNFACTS 2006, 10, 1008.

1. Swager, T. M.; Chan, J. M. W. “Synthesis of a Poly(sulfamide) from Sulfur Dioxide”, SYNFACTS 2006, 9, 0902.


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